Body surface (Total 740857 Papers Found)

Feline calicivirus (FCV) is a positive-strand, nonenveloped RNA virus in the family Caliciviridae. A cDNA library of the Urbana (URB) strain of FCV was generated and the sequence of the genome was determined from overlapping clones except for 13 bases from the 5'-end. The 5'-end sequence was identified by analysis of clones derived by RT-PCR across the ligated 5'- and 3'-ends of the RNA genome. A full-length cDNA clone of the RNA genome of the URB strain was constructed and placed downstream of ...
Thermal injury-associated specific immune deficiency occurs despite indicators of systemic activation of the lymphoid compartment. We investigated the possibility that postburn immune failure and T cell activation are causally related through activation-induced (apoptotic) cell death. The relationship between the cellular immune response and cell mortality was examined in cultures of peripheral blood mononuclear cells (PBMC) from 14 immunosuppressed patients with extensive burns (35–90% total ...
We surveyed the epidemiology of the patients in a tertiary burn care centre (the Motahari Burn Hospital) in Tehran in the 4-yr period 2005-2009. Scalding was the major cause of burn injury for patients under the age of 6, while there were many more flame and electrical burns in late childhood. Males were mainly affected (male to female ratio, 1.7:1). Most burns occurred in the summer, probably due to older children's increased outdoor activities during school vacations. Most of the injuries took ...
The feline kidney cell line CrFK is used extensively for viral infectivity assays and for study of the biology of various retroviruses and derived vectors. We demonstrate the production of an endogenous, RD114-like, infectious retrovirus from CrFK cells. This virus also is shown to efficiently package Moloney murine leukemia virus vectors. ...
Contact with hot oven doors is an important cause of burns in pediatric patients. These burns are of particular concern because of their frequent localization to the hands, with the resulting negative implications for financial cost, long-term cosmesis, and hand function. A 5-year review of pediatric oven door burn cases admitted to a burn referral center was conducted. Of the 14 cases identified, the median age was 12 months. The median total body surface area (TBSA) was 1.75% (range, 0.5%-4.5% ...
PURPOSE Evaluation of vitamin D (vD) status and risk factors for low vD among breastfeeding mother-infant dyads in a population at high risk for vD deficiency. SUBJECTS AND METHODS We measured serum 25-hydroxyvitamin D (25(OH)D) and parathyroid hormone at 1 month postpartum in 60 consecutive exclusively breastfeeding Arab mother-infant dyads enrolled in a high dose vD supplementation study to prevent vD deficiency in Doha, Qatar, (latitude 25°N) during summer months. Data were collected on de ...
A moderately halophilic, slightly acidophilic, aerobic bacterium, designated strain YTM-1(T), was isolated from the body surface of Malacocottus gibber. Cells were Gram-stain-negative, short rods or cocci, approximately 0.9-1.1 µm long and 1.0-1.8 µm wide. Strain YTM-1(T) was able to grow with 1-30% NaCl (optimum, 7.5-10%, w/v), at 4-30 °C (optimum, 20-25 °C) and at pH 3.8-9.5 (optimum, pH 5.0-5.5). Phylogenetic analysis based on 16S rRNA gene sequence similarities showed that strain YTM-1(T ...
OBJECTIVE This study analysed the epidemiology of burns in the elderly in Sichuan Province, China, with the objective of formulating a prevention programme. METHODS A retrospective review of elderly patients admitted to the Burn Centre of West China Hospital during 2003-2009 was performed, including patient demographics, education and burn aetiology. RESULTS A total of 103 patients, mean age 69.5 years (range 60-95 years; 58 male, 45 female) were admitted. The most common causes of burn were ...
OBJECTIVE Diastolic dysfunction in hypertensive patients with preserved left ventricular (LV) ejection fraction (EF) (>40%) could be associated with prolonged systolic contraction and delayed systolic relaxation. We therefore examined whether time to peak systolic myocardial wall stress (MWS) relates to diastolic dysfunction. DESIGN AND METHOD We studied 178 subjects, evaluated for hypertension but otherwise free of clinically apparent cardiovascular disease aged 45.8 ± 16.3 (mean ± ...
It is well known that the marked hypermetabolic response of the human body to thermal injury requires aggressive nutritional support. In order to minimize catabolic conditions resulting in severe weight loss, an oral hyperalimentation regimen has been successfully implemented in the burns unit of Tygerberg Hospital, Cape Town. Ninety-eight patients with deep burns, varying from 20 per cent to more than 60 per cent of body surface area, were included in this study. The results indicated a general ...
The effect of burn injury on blood sugar levels, serum insulin levels and glucose tolerance was studied in male rats. In the burned group (following 50 per cent surface burn injury), the blood sugar level was significantly increased after burn injury in comparison with control uninjured rats. Hyperglycaemia was blocked by injection of phentolamine (10 mg/kg) for 24 h or propranolol (50 micrograms/kg) 30 min before burn or if the animals were adrenalectomized 4 days before injury. Serum insulin l ...
Recently, it has been shown that G protein-coupled receptors (GPCRs) display intrinsic voltage sensitivity. We reported that the voltage sensitivity of M2 muscarinic receptor (M2R) is also ligand specific. Here, we provide additional evidence to understand the mechanism underlying the ligand-specific voltage sensitivity of the M2R. Using ACh, pilocarpine (Pilo), and bethanechol (Beth), we evaluated the agonist-specific effects of voltage by measuring the ACh-activated K+ current (I KACh) in feli ...
OBJECTIVES To evaluate the long-term survival of patients undergoing aortic root enlargement (ARE) compared with those with small aortic root (SAR), exploring risk factors for late mortality as well as the influence of patient-prosthesis mismatch (PPM). METHODS From January 1999 through December 2010, a total of 3724 patients underwent isolated or combined aortic valve replacement at our institution. From these, 239 (6.4%) had transannular ARE with a pericardial patch, to permit implantation o ...
Serum creatinine (Scr) is the most frequently used test to estimate graft function after kidney transplantation. Our previous study demonstrated that the independent predictors of recipient posttransplantation Scr included the ratio of graft weight to recipient body weight, the ratio of graft weight to recipient body surface area (BSA), and the ratio of graft weight to recipient body mass index (BMI). A prospective analysis about the impact of the balance between metabolic demands and renal supp ...
Processes of heat transfer in the skin layer with blood vessels were investigated using mathematical modeling. Analysis of influence of a pathological state of blood vessels on heterogeneity of thermal field of the skin surface was carried out. For each site of body surface, there is a certain difference of temperature between normal and pathological sites, being specific for differential diagnosis of diseases of dermal and hypodermic vessels. ...
Canine parvovirus (CPV) can productively infect canine and feline cell lines whereas feline panleukopenia virus (FPV) is restricted to the latter. The major determinants of tropism are two amino acids in the sequence shared by the capsid proteins, VP1 and VP2. We have shown that a rodent parvovirus-derived transducing genome, containing the luciferase reporter, can be packaged by VP1 and VP2 from separate helper sources. Canine A72 cells and feline CFK cells were transduced with recombinant viri ...
To assess the operative blood loss after tangential excision of burn wounds treated by subeschar infiltration of epinephrine solution, the medical records of 85 consecutive patients were analysed retrospectively. All patients were given epinephrine. The median (range) blood loss was 0.9 (0.3 - 4%) of the blood volume of each patient of the body surface excised and grafted (blood loss from donor sites included). Multiple regression analysis showed strong correlation between the blood loss and the ...
OBJECTIVE There has been an explosive increase in our understanding of the natural history and progression of CAD in women. Women have a poorer prognosis and a more severe outcome than men after myocardial infarction, Percutaneous transluminal coronary angioplasty (PTCA) and coronary artery bypass grafting (CABG). The purpose of the present study was to evaluate the differences in the results of CABG in women as compared with men using Pump and Off Pump operating techniques. METHODS Data of 35 ...
Original technique is described of recording radiative convective heat flow- (RCHF) over various sites of the patient's body surface while he or she is receiving a mud treatment. The dynamics of the RCHF in the course of applying mud to the patient is demonstrated, which is best recorded over the surfaces of the forehead and hands. The proposed technique permits the objectivization of thermoenergetic response of the organism to thermal therapeutic interventions to be done. ...
OBJECTIVE To investigate the distribution pattern, species diversity and community structure of fleas on small mammals in the surrounding area of Erhai Lake, and the relationship between fleas and their hosts. METHODS Different geographical areas surrounding the Erhai Lake in Yunnan were selected as investigated spots. Small mammals were captured with baited cages. The cage-traps were examined and re-baited each morning. All fleas on the hosts were collected and identified. The richness (S), e ...
Sunitinib is an inhibitor of platelet-derived growth factors receptor (PDGFR) and vascular endothelial growth factor receptor-2 (VEGFR2) tyrosine-kinase activities, and it is registered for the treatment of metastatic renal cell carcinoma (mRCC). Indeed, sunitinib 50mg/day for 28 days every 6 weeks is effective against mRCC and induces significant improvements in progression-free and overall survival (PFS and OS, respectively) with respect to interferon-α and interleukin-2, even in cytokine-res ...
ST segment elevation in right precordial leads is thought to be a good predictor of right ventricular involvement in patients with acute inferior myocardial infarction. This view, however, is rapidly disappearing. Therefore, using QRS changes in body surface potential maps in the chronic phase, we have attempted to differentiate patients with or without right ventricular involvement. Thirty patients with chronic inferior myocardial infarction (2 or more months after onset) were studied, in whom ...
OBJECTIVE To establish local normative data of thyroid volume assessed by ultrasonography in subjects aged 0-55 years living in İstanbul, Turkey. METHODS Subjects without any known history of thyroid disease, of major surgery and/or chronic disease were enrolled in the study and evaluated by physical examination and thyroid ultrasonography. Thyroid gland and isthmus at usual location, each lateral lobe volume with three dimensions, ectopic thyroid tissue and echogenicity of the gland were ass ...
To the Editor: Topical analgesics have been well studied in the management of neuropathic pain, however, limited data are present on their role in treating pruritus. Although noted improvement was seen with low concentrations of topical ketamineamitriptyline in the therapy of localized itch, there are no studies to our knowledge examining the combination of topical ketamine-amitriptylinelidocaine (TKAL) on chronic itch with validated tools. Its proposed mechanism of action is aimed at reducing h ...
Protein kinase CK2 (CK2) is a highly promising target for cancer therapy, and anti-CK2 gene expression therapy has shown effectiveness in rodent models of human head and neck cancer (HNC). To date, there has been no large-animal model of cancer in which to further explore anti-CK2 therapies. Feline oral squamous cell carcinoma (FOSCC) has been proposed as a large-animal model for human HNC, and we have previously shown that CK2 is a rational target in FOSCC. Here we have tested the hypothesis th ...
  • W. .,
  • Archiv für Psychiatrie und Nervenkrankheiten
  • 2005
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This study examined the hypothesis that burn injury inhibits the release of splanchnic PGI2, a potent endogenous vasodilator of the splanchnic vascular bed. Male Hartley Guinea Pigs (350 grams) were anesthetized, shaved and subjected to a full thickness scald burn comprising 45% of the total body surface area (or sham burn). The animals were treated with intravenous or topical lazaroid, a 21-aminosteroid U75412E. After recovery for 24 hours, the animals were anesthetized, and the superior mesent ...
Background: Thalassemia major (TM) is a hereditary disease with synthesis defects in beta chains of haemoglobin. Thalassemia major causes red blood cell destruction, leading to anemic symptoms and need for regular blood transfusions. Ferritin which is a diagnostic marker of iron overload in thalassemia patients increases due to inadequate erythropoiesis, iron overload, transfusion, and increased GI absorption. High serum ferritin levels increase the risk of myocardial infarction in thalassemic p ...
OBJECTIVE This study aimed to compare the correlations between KT/V and creatinine clearance (Ccr) calculated by different methods and to determine and compare the correlations between KT/V and Ccr. DESIGN Nonrandomized, retrospective analysis of data. SETTING Continuous ambulatory peritoneal dialysis (CAPD) outpatient clinic in a teaching hospital. PATIENTS All patients were included for analysis if the data collection was complete for the calculations of KT/V and Ccr using five different ...
A recombinant retroviral subunit vaccine has been developed that successfully protects cats from infectious feline leukaemia virus (FeLV) challenge. The antigen used is a non-glycosylated protein derived from the envelope glycoprotein of FeLV subgroup A, expressed in Escherichia coli. This recombinant protein, rgp70D, includes the entire exterior envelope protein gp70, plus the first 34 amino acids from the transmembrane protein p15E. The vaccine consists of purified rgp70D absorbed on to alumin ...
The purpose of this study was to examine the possible influence of age on thermogenic response to a mixed meal in healthy subjects. Twenty-five healthy male subjects participated in the study and they were divided into three groups, comprising 10 young subjects with an average age of 27 years (22-35 years), seven middle-aged individuals (51 years, 42-60 years) and eight elderly men (70 years, 67-74 years). They were all studied with continuous indirect calorimetry in the basal state and for 3 h ...
BACKGROUND AND AIMS This study aimed to investigate the influence of enteral glutamine (GLN) supplementation on Peyer's patch apoptosis in severely burned mice. METHODS Thirty-four mice were randomly assigned to a normal group (n=10), an EN group (n=12) and an EN supplemented with GLN (EN+GLN) group (n=12) and the mice in the EN and EN+GLN groups received a full-thickness scald burn over 20% total body surface area (TBSA) on the back. The burned mice then were fed orally with a common EN or an ...
OBJECTIVE To investigate the clinical effect of Meek technique skin graft in treating exceptionally large area burns. METHODS The clinical data were retrospectively analysed from 10 cases of exceptionally large area burns treated with Meek technique skin graft from April 2009 to February 2010 (Meek group), and were compared with those from 10 cases of exceptionally large area burns treated with the particle skin with large sheet of skin allograft transplantation from January 2002 to December 2 ...
Objectives This study assessed behavioral and physiologic stress parameters in cats placed in two environments: home and the veterinary hospital. With a widely used scale, several parameters were assessed, including respiratory rate (RR), heart rate (HR), systolic blood pressure (SBP), vagosympathetic responses using calculated intervals (heart rate variability [HRV]10, HRV20 and vasovagal tonus index [VVTI]) and 'stress attitude', such as struggling, vocalization and agitation during handling. ...
Living donor and split-liver transplantation techniques require the calculation of a standard liver volume (SLV) as a reference point for the minimal volume necessary for the recipient. We therefore examined whether a widely used formula developed on the basis of a Japanese population sample was also adequate for the Caucasian population. The documentation of volumes of 1332 autopsy livers from a German Forensic Medicine Department was used to create a formula for an SLV for the Caucasian popula ...